What Is EBOO Therapy?
One of the most involved forms of ozone therapy — your blood passes through a closed circuit, is exposed to ozone and oxygen, and is returned. Available right here in North Charleston, SC.
EBOO: The “Ferrari of Ozone Therapy”
EBOO stands for Extracorporeal Blood Ozonation and Oxygenation. Blood is drawn from the body, passed through a medical-grade device with a diffuser, exposed to medical-grade ozone and oxygen, then returned to your veins. Researchers are still exploring what effects this may have.
Unlike standard IV ozone therapies that treat only a small volume of blood, EBOO processes a substantially larger volume through a closed, sterile circuit — which is one way it differs from standard IV ozone.
Blood Drawn
Blood exits via IV line into the EBOO device’s sterile circuit.
Diffused
Blood passes through a diffuser in the closed circuit.
Ozonated
Medical-grade ozone and oxygen diffused into the blood.
Returned
Your blood returns to your body through the second IV line.
Is EBOO Therapy Right For You?
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What Patients Report After EBOO Therapy
More Energy
Some patients tell us they feel more energy and stamina afterward. Everyone responds differently.
Questions About Inflammation
Researchers are exploring how EBOO may relate to inflammation; it has not been proven to lower inflammation.
Immune Support
Researchers are exploring how ozone may interact with immune pathways, and EBOO is not FDA-approved to treat infections or any condition.
Cognitive Clarity
Some patients tell us they feel clearer and more focused afterward. Everyone responds differently.
Feeling Recovered
Some active patients tell us they feel recovered sooner after hard training. Everyone responds differently.
Questions About Toxins
People living with mold illness, Lyme, or Epstein-Barr often ask whether the diffusion step removes toxins; that has not been proven, and research is still early.
How EBOO Compares to Other Ozone Therapies
| Feature | Standard IV Ozone | EBOO Therapy |
|---|---|---|
| Blood Volume Treated | 50–250 mL | Significantly larger volume |
| Diffusion Step | ❌ None | ✅ Medical-grade diffuser |
| Two IV Lines (Draw and Return) | ❌ No | ✅ Yes |
| Session Length | 30–45 min | 60–90 min |
| Comprehensiveness | Moderate | High — most thorough ozone option |
| Availability in Southeast | Widespread | Very limited — few clinics offer it |
Frequently Asked Questions About EBOO Therapy
What is EBOO therapy?
EBOO (Extracorporeal Blood Ozonation and Oxygenation) is a dialysis-like procedure that removes blood from the body, passes it through a medical-grade diffuser, infuses it with ozone and oxygen, then returns it to your body. It is often called the most comprehensive form of ozone therapy available.
How is EBOO different from regular IV ozone therapy?
Standard IV ozone treats a small blood volume with no diffusion step. EBOO processes significantly more blood through a medical-grade diffuser in a closed circuit. Researchers are still exploring how the two methods compare.
What conditions is EBOO therapy used for?
People living with chronic fatigue, long COVID, Lyme disease, mold exposure, Epstein-Barr virus, autoimmune conditions, and systemic inflammation often ask us about EBOO. EBOO is not FDA-approved to treat any of these conditions, and research is still early, so your provider will talk through whether it may fit your overall plan. It is also used as part of anti-aging and regenerative medicine protocols for patients seeking whole-body optimization.
Is EBOO therapy safe?
EBOO is not risk-free, so it is done only by trained practitioners in a supervised clinical setting after screening, and your provider will review possible side effects with you. Charleston Pain Relief Center reviews every patient’s health history before treatment. Sessions run 60–90 minutes in a comfortable, monitored environment.
What does EBOO therapy feel like?
Most patients describe the session as comfortable and relaxing. You sit or recline with two IV lines — one drawing blood, one returning it — for 60–90 minutes. Some patients report feeling more energized within hours to days following treatment; everyone responds differently.
How many EBOO sessions will I need?
Most patients begin with a series of sessions as part of an ongoing wellness routine. The exact number depends on your health history and goals. Your care team at Charleston Pain Relief Center will build a personalized protocol during your initial consultation.
Can EBOO be combined with other treatments?
Yes — many people pair EBOO with stem cell therapy, PRP and other regenerative treatments, based on their provider’s plan. Researchers are still exploring how EBOO and regenerative therapies may work together, and results vary. Many CPRC patients combine both in a single protocol.
Where can I get EBOO therapy in South Carolina?
Charleston Pain Relief Center at 2294 Otranto Rd, North Charleston SC 29406 is one of the few clinics in the Southeast offering EBOO therapy. Patients travel from across the Carolinas, Georgia, Virginia, and beyond. Call 843-604-2276 or visit our service page to book.
Ready to Learn If EBOO Is Right for You?
Visit our full EBOO service page to see our protocol, pricing, and how to book — or call our team at 2294 Otranto Rd, North Charleston SC 29406.
Ready to picture the visit? What to expect during your first EBOO session →