EBOO therapy—short for Extracorporeal Blood Oxygenation and Ozonation—has rapidly emerged as one of the most advanced and comprehensive wellness therapies available today. Often referred to as EBO2, this treatment detoxifies and oxygenates the blood outside of the body before returning it, helping individuals struggling with chronic illness, inflammation, and fatigue experience a renewed sense of health and energy.
In this article and accompanying podcast, we explore the latest findings and expert insights on EBOO therapy, highlighting its core benefits, how it works, and its growing role in supporting recovery from chronic health conditions.
Listen to our Podcast : A Complete Briefing on Benefits, Mechanism, and Chronic Illness Support
Main Themes:
- Advanced Blood Cleansing and Oxygenation: EBOO is consistently presented as an innovative and advanced therapy focused on detoxifying and hyperoxygenating the blood outside the body before returning it to the patient.
- Multi-faceted Approach: Several sources highlight that EBOO often involves more than just ozone therapy, frequently incorporating filtration, various light therapies (UV and full-spectrum LED), and sometimes other additions like hydrogen and bioactive carbon.
- Potential for Treating Chronic Conditions: A significant theme revolves around EBOO’s potential benefits for a wide range of chronic illnesses, particularly those involving inflammation, infection, and impaired detoxification. Conditions frequently mentioned include Lyme disease, Epstein-Barr virus, mold toxicity, heavy metal toxicity, chronic fatigue syndrome, autoimmune conditions, and long COVID symptoms.
- Enhanced Energy and Well-being: Beyond specific conditions, EBOO is also promoted for general health and wellness, anti-aging, boosting energy levels, improving mental clarity, and enhancing immune function.
- Comparison to Other Ozone Therapies: Sources often differentiate EBOO from traditional ozone therapies like Major Autohemotherapy (MAH) and 10-pass ozone, emphasizing EBOO’s higher volume processing and potentially gentler delivery.
- Growing Popularity and Limited Availability: While EBOO is described as gaining popularity, the sources suggest that it is still a relatively new treatment with a limited number of practitioners, particularly in the United States.
- Importance of Experienced Practitioners: The success and safety of EBOO are linked to the expertise of the healthcare providers administering the therapy.
Most Important Ideas and Facts:
Definition and Mechanism: EBOO involves extracting blood from a patient, treating it with ozone and oxygen (and often filtration and light therapies), and then returning the treated blood to the body. Amy Bickford describes EBO2 as “extra corporeal blood oxygenation and ozonation and it is the most advanced Medical ozone therapy currently available.
“Dr. Dan Rubin states, “Ebu eb00 or extra corporio blood oxygenation and ozonation were taken two liters of blood out over the course of 50 minutes we’re processing it… the blood comes comes in here moves up through the column there’s a tube that feeds ozone and oxygen into the blood… and then this beautiful machine adds uh full spectrum LED and full spectrum UV.”
Dr. Nario explains, “It’s extra corporeal blood ozonation and oxygenation.”
Dr. Yoshi Rahm clarifies, “Ebu stands for extracorporeal blood oxygenation and ozonation so you can a lot of people think of it as like a dialysis and that’s really just because we have blood coming out of one arm going through this machine and then coming back into the other arm it’s not dialysis at all it’s really just how do we get this huge surface area of our blood exposed to the oxygen ozone mixture.”
Filtration: Some EBOO protocols invert a dialysis filter to target larger particles like “heavy metals, cholesterol, petroleum byproducts, cellular waste and disease,” as mentioned by Amy Bickford. Ozone is then added to further help pull out these particles and eliminate pathogens.
Dr. Nario also highlights using a “dialysis filter to clean the blood from debris of destroyed germs heavy metals fungus and more.”
Ozone Therapy: Ozone hyperoxygenates the blood, helps eliminate molds, viruses, and bacteria, and removes inflammatory proteins like beta 2 microglobulins (Amy Bickford).
Dr. Rubin mentions delivering “about a hundred and fifty thousand micrograms of ozone” in their EBOO treatment.
Light Therapy: Many EBOO systems incorporate hemolumin light therapy (UVA, UVC, red, blue, green, amber) to further help remove pathogens and stimulate mitochondrial function (Amy Bickford). Dr. Rubin and Dr. Nario also mention using full-spectrum LED and UV light.
Dr. Yoshi Rahm emphasizes the full spectrum of light used in their EBOO, including UVA, UVB, UVC, visible light, and near-infrared, suggesting a synergistic effect with ozone. He notes, “…if we can just take some of that and take a little sunlight and put it in a box and add it into this Ebu therapy there seems to be this Synergy.”
Volume of Blood Treated: EBOO typically processes a significantly larger volume of blood compared to other ozone therapies.
Amy Bickford states that while a 10-pass might filter a maximum of two liters, “eb02 has the capacity to filter four to seven liters of blood potentially surpassing the total blood volume of the average person.”
Dr. Rubin mentions treating “up to two liters” of blood.
Dr. Nario describes two session types: one liter over 25 minutes for sensitive patients and two liters over 50 minutes for most.
Benefits for Specific Conditions: Several sources list conditions that may benefit from EBOO:
Amy Bickford: “patients with Epstein-Barr Lyme disease heavy metal toxicity mold toxicity long covid symptoms autoimmunity and chronic inflammation can benefit from eb02.”
Charleston Pain Relief Center: “Many individuals suffering from chronic conditions such as Mold Exposure, Epstein-Barr, Chronic Lyme, and Chronic Fatigue Syndrome have found relief through this innovative therapy.”
They also list chronic fatigue, inflammation-related issues, autoimmune conditions, cancer (as a potential aid), low energy, weak immune system, detoxification needs, recovery from chronic illness, Lyme disease, and more.
Dr. Yoshi Rahm mentions anecdotal improvements in autoimmune conditions, brain fog, Crohn’s, and colitis.
General Wellness Benefits: EBOO is suggested to support general health, wellness, and healthy aging (Amy Bickford), boost oxygen levels, enhance immune function (Charleston Pain Relief Center), improve energy, and promote overall well-being.
Dr. Rubin highlights benefits for “energy antimicrobial anti-aging skin changes… your immune system.”
Charleston Pain Relief Center lists enhanced detoxification, improved oxygenation, boosted immune function, effective pain relief, and anti-aging effects.
Comparison to 10-Pass Ozone: Amy Bickford notes that EBO2 can filter a much larger volume of blood than a 10-pass. Dr. Yoshi Rahm suggests EBOO delivers a gentler dose of ozone compared to the higher concentrations used in a 10-pass, potentially leading to better tolerability.
Frequency of Treatment: Recommendations vary, but Amy Bickford suggests once a week for three to four weeks for chronic conditions, and every three to four months for general wellness. Dr. Nario recommends an initial three sessions one week apart, repeated a few times a year. Dr. Yoshi Rahm suggests weekly sessions initially, then moving to every two to three weeks, and eventually quarterly for maintenance.
Safety and Side Effects: EBOO is generally described as a relatively safe and non-invasive treatment with minimal side effects (Charleston Pain Relief Center). Dr. Yoshi Rahm mentions the possibility of a vasovagal response due to fear of blood. Heparin is often used to prevent clotting during the procedure. Contraindications mentioned by Dr. Yoshi include heparin allergy, pregnancy (primarily due to liability), and untreated G6PD deficiency or hyperthyroidism (with caution).
Filter Contents: While some believe the filter collects significant toxins, Dr. Yoshi Rahm offers a more nuanced perspective: “my take after listening to trying to keep up on all the blogs and everything and sending in some tests ourself and listening to what other doctors uh may have done…
Is that there definitely is junk that is collected in that… but my question and what I don’t well my question is how clinically useful is that because I don’t believe that there’s that much being taken out and the blood is just a small portion of our body…”
Mental Clarity and Energy: Dr. Yoshi Rahm’s small study indicated subjective improvements in mental clarity, energy, drive, sleep quality, and digestion in patients undergoing EBOO.
Growing Availability: Dr. Yoshi Rahm notes that while EBOO was once very rare in the US, it is gaining popularity with more practitioners offering the treatment.
Quotes Highlighting Key Aspects:
On the advanced nature: Amy Bickford: “…it’s eb02 eb02 stands for extra corporeal blood oxygenation and ozonation and it is the most advanced Medical ozone therapy currently available.”
On the multi-faceted approach: Amy Bickford: “multifaceted there’s a few components to eb02 there’s the dialysis filter ozone therapy and hemolumin light therapy and there’s major benefits to all of these combined.”
On the potential for chronic conditions: Charleston Pain Relief Center: “Many individuals suffering from chronic conditions such as Mold Exposure, Epstein-Barr, Chronic Lyme, and Chronic Fatigue Syndrome have found relief through this innovative therapy.”
On the volume of blood treated: Amy Bickford: “…eb02 has the capacity to filter four to seven liters of blood potentially surpassing the total blood volume of the average person…”
On the synergistic effect of light: Dr. Yoshi Rahm: “…if we can just take some of that and take a little sunlight and put it in a box and add it into this Eboo therapy there seems to be this Synergy.”
On the question of filter contents: Dr. Yoshi Rahm: “…is it definitely takes out some of that but my question and what I don’t well my question is how clinically useful is that because I don’t believe that there’s that much being taken out and the blood is just a small portion of our body…”
On patient-reported benefits: Dr. Yoshi Rahm: “…all of those other ones the mental Clarity the energy the drive the Sleep Quality and then actually digestion which surprised me because that was the the biggest benefit all of them either tracked as no improvement but much more often than no improvement was Improvement…”
On a striking benefit: Dr. Nario: “see the most prominent one that I really have seen even comparing it to other eye visas number one Pain Relief pain relief is something that I’ve seen that after the session uh just like a back pain or a knee pain suddenly got better that quick…”
