Is EBOO Therapy Safe? Side Effects & What to Expect
A straight, honest answer about EBOO ozone therapy safety — how it works, who it is not for, and how we keep it safe at our North Charleston clinic.
Short answer: for most healthy adults, EBOO is well tolerated when it is performed by trained providers who screen you first, use sterile single-use equipment, and monitor you throughout. The ozone is combined with your blood outside the body in a controlled medical setting — it is never inhaled. As with any therapy, safety depends on proper screening and technique, and EBOO is not right for everyone. Below is exactly what to expect, the possible side effects, and who should avoid it.
What makes EBOO safe when it is done right
EBOO (Extracorporeal Blood Oxygenation and Ozonation) draws a small, continuous flow of blood, passes it through a filter, adds medical ozone and oxygen, and returns it to you. Four things make that safe:
- Health screening first. We review your history, medications, and conditions before your first session to confirm EBOO is appropriate for you.
- Sterile, single-use equipment. The tubing and filter are new for every patient, which removes cross-contamination risk.
- Controlled, external process. Ozone is only added to blood outside the body. It is never breathed in, which is where ozone can be harmful.
- Monitoring throughout. Trained staff stay with you and watch how you respond for the whole session.
Possible side effects of EBOO
Most side effects are mild and temporary. They can include:
- Temporary tiredness or low energy for a few hours
- Mild lightheadedness, especially if you came in dehydrated or hadn’t eaten
- A cool sensation as filtered blood returns to you
- Minor bruising or soreness where the IV lines are placed
- A brief “detox” or Herxheimer-type reaction — a mild flu-like feeling as your body clears toxins — that usually settles within a day
Serious reactions are rare when EBOO is properly screened and administered. Drinking water and eating beforehand makes the session more comfortable.
Who should NOT get EBOO therapy
EBOO is not appropriate for everyone. We do not perform it if you are:
- Pregnant or breastfeeding
- Living with G6PD deficiency (favism)
- Managing an active bleeding or clotting disorder
- Dealing with uncontrolled hyperthyroidism
- Recovering from a recent heart attack or stroke
If you take blood thinners or have a serious heart, lung, or blood condition, tell us up front so we can screen you carefully — and we will be honest if EBOO is not a good fit for you.
Is EBOO FDA approved?
No. The U.S. Food and Drug Administration has not approved ozone therapy to treat, cure, or prevent any disease. We are transparent about that. We offer EBOO as a wellness therapy for people who want to explore it, and we will always give you an honest picture of what it can and cannot do before you book.
How we keep your EBOO session safe
Screen your history → use sterile single-use tubing and filters → add ozone only outside the body → monitor you the whole time → tell you honestly if you are not a candidate. That is the whole safety framework, and none of it is optional.
EBOO safety FAQ
Is EBOO therapy safe?
For most healthy adults, EBOO is well tolerated when it is done by trained providers who screen you first, use a sterile single-use kit, and monitor you throughout the session. Safety comes down to proper screening and technique — which is why we review your health history before your first session.
What are the side effects of EBOO?
Most side effects are mild and short-lived: temporary tiredness, mild lightheadedness, a cool sensation as blood returns, or slight bruising at the IV site. Some people feel a brief “detox” or Herxheimer-type reaction (mild flu-like feeling) as the body clears toxins. These usually pass within a day.
Does EBOO hurt?
You will feel a small pinch when the IV lines are placed, similar to a blood draw. After that most patients relax, read, or nap. It is not a painful treatment.
Who should not get EBOO therapy?
EBOO is not appropriate for everyone. We do not treat people who are pregnant or breastfeeding, have G6PD deficiency (favism), active bleeding or clotting disorders, uncontrolled hyperthyroidism, or a recent heart attack or stroke. If you take blood thinners or have a serious heart, lung, or blood condition, tell us so we can screen you carefully.
Is ozone therapy dangerous?
Ozone is only unsafe when it is inhaled or used incorrectly. In EBOO, ozone is added to blood outside the body in a controlled, medical setting — it is never breathed in. Trained administration and screening are what keep it safe.
Is EBOO therapy FDA approved?
No. The U.S. FDA has not approved ozone therapy to treat, cure, or prevent any disease. We offer EBOO as a wellness therapy, and we are transparent about that so you can make an informed choice.
How many EBOO sessions are safe to have?
Most people do a short series rather than a single session, spaced out over weeks. Your provider will recommend a schedule based on your health and goals. There is no fixed universal limit — it is guided by how you respond.
How do you keep EBOO safe at your clinic?
We screen your health history first, use sterile single-use tubing and filters, follow careful protocols, and monitor you the whole time. If anything about your history suggests EBOO is not a good fit, we tell you honestly before booking.
Learn more about EBOO
This page is for general education and is not medical advice. EBOO / ozone therapy is not FDA-approved to treat, cure, or prevent any disease; individual suitability and results vary. Talk with our team about your specific health history before starting. Charleston Pain Relief Center · 2294 Otranto Rd, North Charleston, SC 29406 · 843-604-2276.