Short answer
EBOO therapy, explained simply: your blood flows out of one arm through an IV line, passes through a special diffuser where it meets ozone, goes under full-spectrum light, and flows back into your other arm. You rest in a comfy recliner the whole time.
Many people choose EBOO as part of a wellness and longevity routine. At Charleston Pain Relief Center in North Charleston, SC, it starts with a free wellness call and simple labs, so every question gets answered before your day.
Please know: EBOO is a wellness service. Ozone therapy is not FDA-approved to diagnose, treat, cure or prevent any disease. Everyone responds differently.
What does EBOO stand for?
EBOO stands for extracorporeal blood oxygenation and ozonation. That is a mouthful, so here it is one word at a time:
- Extracorporeal means outside the body.
- Blood oxygenation means your blood is exposed to medical oxygen.
- Ozonation means your blood is exposed to a measured amount of ozone, a form of oxygen.
Put together, the name simply describes what happens: your blood meets oxygen and ozone outside your body and then comes back to you. It names the process, not a promised result.
How EBOO works, start to finish
Think of EBOO as a slow, gentle loop. Here is the path your blood takes:
- Out. Blood leaves through an IV line in one arm.
- Diffuser. It passes through a special diffuser, where it meets the oxygen and ozone mix.
- Light. At our clinic, it then passes under full-spectrum light.
- Back in. It returns through a second IV line in your other arm.
A few liters of blood move through this loop over the course of the session. Only a small amount is outside your body at any moment. Our team watches the flow the whole time, and you can talk, read or nap.
Where EBOO came from
A research team in Siena, Italy, first used the name EBOO in a 2000 report. Since then, clinics around the world have offered versions of it. You may also see it called EBO2. It is the same idea with a newer spelling (here is how EBOO and EBO2 compare).
How EBOO compares with other ozone options
You may hear about other ozone methods, such as major autohemotherapy (often called MAH) or a “10-pass.” In those, a set amount of blood is drawn into a bag or bottle, mixed with ozone, and given back, sometimes several rounds in a row.
EBOO works differently. The blood flows in a steady loop through a diffuser instead of a bag, and more blood moves through over one session. Your provider can explain which option fits your goals.
Why do people ask about EBOO?
Most people who call us want to feel their best and invest in healthy aging. Others are living with a long-term health concern and want to know if EBOO could fit alongside the care they already get. Here is what we can share honestly:
- Researchers are exploring how ozone interacts with blood, mostly in small studies.
- Much of what you read online comes from practitioner reports, which raise good questions and give no firm answers.
- Large, high-quality studies of EBOO in people are still limited.
Some patients tell us they feel more energy or clearer after a session, and many love the restful day. Everyone responds differently. If you see a doctor for a health condition, keep taking your medicines as prescribed. With your permission, we coordinate with your other doctors and share your lab results.
Your EBOO day at CPRC, step by step
Here is what a full EBOO visit looks like at our clinic.
- Free wellness call. We get to know you, answer your questions and go over your health history. Nothing gets booked until you feel ready.
- Quick labs. A simple blood draw checks your CBC, CMP and G6PD. Your provider reviews the results before your EBOO day.
- PEMF mat. Your visit starts on a PEMF mat. Gentle magnetic pulses help you settle in and relax.
- EBOO with full-spectrum light. We place two IV lines, one out and one in. A few liters of your blood loop slowly through a special diffuser, where it meets ozone, then pass under full-spectrum light and flow back to you. You rest in a comfy recliner the whole time.
- NEO red light bed. Next, you unwind in our NEO red light bed. Many people say this is their favorite part.
- IV. An IV gives you fluids and nutrients before you head out.
- Power Plate. You finish with a few minutes of gentle vibration on the Power Plate to get you up and moving for the trip home.
EBOO at Charleston Pain Relief Center is overseen by Kayla Blann, FNP-C. Want more detail? Read our full EBOO guide.
Who EBOO is not a good fit for
Your provider screens everyone before EBOO. That is what the labs and the health history are for. EBOO is not a good fit if you:
- Have a bleeding or clotting condition
- Are pregnant
- Have G6PD deficiency (the G6PD lab checks for this)
If you are fighting a cold, have a recent infection or feel unwell on the day, tell us. Your provider may suggest moving your visit. You can read more on our EBOO safety page.
Coming from out of town? You are in good company
More than half of our EBOO patients travel to see us, and we love that. We help you plan your labs, your visit and your timing, so the trip feels easy. Our clinic is at 2294 Otranto Rd in North Charleston, SC, close to I-26 and the airport. Bring all your questions. We enjoy answering them.
Frequently asked questions
What is EBOO therapy in simple terms?
Your blood flows out through one IV line, passes through a special diffuser where it meets ozone, goes under full-spectrum light, and flows back in through a second line. You rest the whole time.
Is EBOO the same as dialysis?
No. EBOO uses a diffuser that looks like a dialysis cartridge, and the blood flows out and back in a similar way. Dialysis is a kidney treatment. EBOO is a wellness service.
Is EBOO FDA-approved?
No. EBOO is offered as a wellness service, and ozone therapy is not FDA-approved for any condition. Many people choose it as part of a wellness and longevity routine.
Does EBOO hurt?
Most people feel two quick pokes when the IV lines go in. After that, you sit back in a recliner and relax while the loop runs.
How often do people do EBOO?
It depends on your goals, your labs and how you feel. Your provider talks through a plan with you. There is no one schedule for everyone.
Can I come from out of town?
Yes. More than half of our EBOO patients travel to see us, and we help you plan your labs and your visit.
Curious how EBOO works? Ask us anything.
Text us at 843-604-2276 — we’ll answer your questions first. Your text is already written. Just press send.
Rather talk it through? Book a free wellness call.
Keep reading
- EBOO therapy in North Charleston: the full guide
- EBOO blood oxygenation: inside the loop
- EBOO safety: what to know
- EBOO vs EBO2: what is the difference?
Charleston Pain Relief Center · 2294 Otranto Rd, North Charleston, SC 29406 · 843-604-2276 · Last updated 30 October 2026. This article is for education and does not replace advice from your own doctor.