Short answer
“EBOO blood oxygenation” describes what happens to your blood outside your body. It flows through a special diffuser, meets medical oxygen and a measured amount of ozone, passes under full-spectrum light and comes back to you through a second IV line.
The name tells you what the machine does to the blood in the loop. It is not a promise about what happens inside your body. At Charleston Pain Relief Center in North Charleston, SC, we walk you through every part of it before your day.
Please know: EBOO is a wellness service. Ozone therapy is not FDA-approved to diagnose, treat, cure or prevent any disease. Everyone responds differently.
EBOO stands for extracorporeal blood oxygenation and ozonation. Extracorporeal means outside the body. The other two words describe what your blood meets while it is out:
The two are blended into one measured gas mix. You may also see EBOO spelled EBO2. It is the same idea (here is how EBOO and EBO2 compare).
The EBOO setup looks a bit like a tall stand with tubing, a diffuser and a light. Here is each part, in the order your blood meets it:
A few liters of blood move through the loop over the session, and only a small amount is outside your body at any moment. Like many systems that move blood outside the body, EBOO usually uses a blood thinner in the tubing so the blood flows smoothly. That is one reason your provider asks about bleeding and clotting. The gas mix goes into the diffuser, not into the air you breathe.
It is easy to read “blood oxygenation” and picture more oxygen reaching every cell. Research has not shown that, so we do not claim it. Here is the plain picture:
Many people choose EBOO as part of a wellness and longevity routine. Some patients tell us they feel more energy or clearer afterward. Everyone responds differently. If you see a doctor for a health condition, keep taking your medicines as prescribed. With your permission, we coordinate with your other doctors.
This is the question we hear most, so here is an honest answer:
If needles make you nervous, let us know ahead of time. We go slowly and talk you through each step.
The loop is one part of a full, relaxing visit. Here is the whole day.
EBOO at Charleston Pain Relief Center is overseen by Kayla Blann, FNP-C. Want more detail? Read our full EBOO guide.
Your provider screens everyone before EBOO. That is what the labs and the health history are for. EBOO is not a good fit if you:
If you have a fear of needles, a recent infection or feel unwell on the day, tell us. Your provider may suggest a plan that makes you more comfortable, or moving your visit. You can read more on our EBOO safety page.
More than half of our EBOO patients travel to see us, and we love that. We help you plan your labs, your visit and your timing, so the trip feels easy. Our clinic is at 2294 Otranto Rd in North Charleston, SC, close to I-26 and the airport.
It means your blood is exposed to medical oxygen and a measured amount of ozone outside your body, inside a special diffuser, and then returned to you. The name describes the process, not a promised result.
Not quite. The oxygen you breathe has two oxygen atoms. Ozone has three. In EBOO, a small, measured amount of ozone is mixed with medical oxygen.
Research has not shown that, so we do not claim it. Researchers are exploring how ozone interacts with blood, mostly in small studies.
The oxygen and ozone mix flows into the diffuser, where it meets your blood. It is not something you breathe in.
You feel two quick pokes when the IV lines go in. After that, most people relax, read or nap. Some feel a little chilly or tired. Tell us and we will help you get comfortable.
Yes. More than half of our EBOO patients travel to see us, and we help you plan your labs and your visit.
Want to see the EBOO loop up close? Ask away.
Text us at 843-604-2276 — we’ll answer your questions first. Your text is already written. Just press send.
Rather talk it through? Book a free wellness call.
Charleston Pain Relief Center · 2294 Otranto Rd, North Charleston, SC 29406 · 843-604-2276 · Last updated 30 October 2026. This article is for education and does not replace advice from your own doctor.
