Short answer
People living with autoimmune conditions and chronic Lyme often ask us about EBOO. The honest answer: EBOO is a wellness service. It is not a treatment for lupus, rheumatoid arthritis, Hashimoto’s, MS, Lyme or any other condition.
Research on ozone and the immune system is early and mostly small. If EBOO interests you, we screen you first and work alongside your specialist. At Charleston Pain Relief Center in North Charleston, SC, your other care always comes first.
Please know: EBOO is a wellness service. Ozone therapy is not FDA-approved to diagnose, treat, cure or prevent any disease. Everyone responds differently.
What is EBOO?
EBOO stands for extracorporeal blood oxygenation and ozonation. “Extracorporeal” just means outside the body. During a session, your blood flows out through one IV line, passes through a special diffuser where it meets ozone, and then flows back in through a second line. At our clinic, it also passes under full-spectrum light on the way back.
A research team in Siena, Italy, first used the name EBOO in a 2000 report. You may also see it called EBO2. It is the same idea with a newer spelling (here is how EBOO and EBO2 compare). People choose it for many reasons. Often it is part of a broader wellness and longevity routine.
Why people with autoimmune conditions ask about EBOO
With an autoimmune condition, the immune system attacks the body’s own tissue. Lupus, rheumatoid arthritis, Hashimoto’s and MS are a few examples. Many people live with tiredness, stiffness and flares that come and go.
That can wear you down. So it makes sense to look for ways to feel better day to day. Many people read about EBOO online and want a straight answer from a real clinic. That is what this page is for.
Does EBOO help autoimmune disease? What research does and doesn’t show
Researchers are studying how ozone interacts with blood cells and the body’s signals. That work is interesting, and it is also early. Here is the plain picture:
- Most studies are small, and many are in labs rather than in people.
- We know of no large, high-quality trials of EBOO for any autoimmune condition.
- Early lab findings do not tell us what EBOO will do for any one person.
Some patients tell us they feel more energy or simply enjoy a restful day of care. Everyone responds differently, and we will never promise a result.
What about EBOO for chronic Lyme?
Many people with lingering Lyme symptoms ask the same questions. The answer is the same too. EBOO is a wellness service, and research on ozone and Lyme is still early. We wrote a full page on it: EBOO for Lyme disease: honest answers.
Your specialist stays in charge
If you see a rheumatologist, neurologist or Lyme doctor, keep working with them. Keep taking your medicines exactly as prescribed, including any that calm the immune system. Bring your full medication list to your wellness call.
With your permission, we are glad to coordinate with your other doctors and share your lab results, so everyone sees the same picture.
What your EBOO day looks like at CPRC
Here is a full EBOO visit, one step at a time.
- Free wellness call. We get to know you, answer your questions and go over your health history. Nothing gets booked until you feel ready.
- Quick labs. A simple blood draw checks your CBC, CMP and G6PD. Your provider reviews the results before your EBOO day.
- PEMF mat. Your visit starts on a PEMF mat. Gentle magnetic pulses help you settle in and relax.
- EBOO with full-spectrum light. We place two IV lines, one out and one in. A few liters of your blood loop slowly through a special diffuser, where it meets ozone, then pass under full-spectrum light and flow back to you. You rest in a comfy recliner the whole time.
- NEO red light bed. Next, you unwind in our NEO red light bed. Many people say this is their favorite part.
- IV. An IV gives you fluids and nutrients before you head out.
- Power Plate. You finish with a few minutes of gentle vibration on the Power Plate to get you up and moving for the trip home.
EBOO at Charleston Pain Relief Center is overseen by Kayla Blann, FNP-C. Want more detail? Read our full EBOO guide.
Who EBOO is not a good fit for
Your provider screens everyone before EBOO. That is what the labs and the health history are for. EBOO is not a good fit if you:
- Have a bleeding or clotting condition
- Are pregnant
- Have G6PD deficiency (the G6PD lab checks for this)
If you are in a flare, have a fever or have just started a new medicine, tell us. Your provider may suggest waiting until you feel steady. You can read more on our EBOO safety page.
Coming from out of town? You are in good company
More than half of our EBOO patients travel to see us, and we love that. We help you plan your labs, your visit and your timing, so the trip feels easy. Bring recent labs and notes from your specialist if you have them. Our clinic is at 2294 Otranto Rd in North Charleston, SC, close to I-26 and the airport.
Frequently asked questions
Can EBOO treat autoimmune disease?
EBOO is a wellness service, not a treatment for autoimmune disease. Some people choose it as part of their wellness routine, alongside the care their specialist provides.
Does EBOO affect the immune system?
Researchers are studying how ozone interacts with blood cells and immune signals. The work is early and mostly small, so it does not tell us what EBOO will do for you.
Can I have EBOO if I take immune medicines?
Possibly. Your provider reviews every medicine you take and your labs before EBOO. Keep taking your medicines exactly as prescribed.
Is EBOO used for chronic Lyme?
Some people with lingering Lyme symptoms ask about EBOO. It is a wellness service, and research on ozone and Lyme is still early. Your Lyme doctor stays in charge of your Lyme care.
What labs do I need first?
We check a CBC, a CMP and G6PD. Kayla Blann, FNP-C, who oversees EBOO, reviews them with your health history.
Do you work with my other doctors?
Yes. With your permission, we coordinate with your other doctors and share your lab results.
Wondering if EBOO fits your plan? Ask us.
Text us at 843-604-2276 — we’ll answer your questions first. Your text is already written. Just press send.
Rather talk it through? Book a free wellness call.
Keep reading
- EBOO therapy in North Charleston: the full guide
- EBOO for Lyme disease: honest answers
- EBOO safety: what to know
- EBOO vs EBO2: what is the difference?
Charleston Pain Relief Center · 2294 Otranto Rd, North Charleston, SC 29406 · 843-604-2276 · Last updated 30 October 2026. This article is for education and does not replace advice from your own doctor.