Short answer
People living with Lyme disease often ask us about EBOO. Here is the honest answer: EBOO is a wellness service, not a Lyme treatment. Research on ozone and Lyme is still early. Most of it is small studies and reports from practitioners.
If you are curious, we start with a free call, screen you with labs, and work alongside the doctor who manages your Lyme care. At Charleston Pain Relief Center in North Charleston, SC, you will know exactly what happens before you book anything.
Please know: EBOO is a wellness service. Ozone therapy is not FDA-approved to diagnose, treat, cure or prevent any disease. Everyone responds differently.
What is EBOO?
EBOO stands for extracorporeal blood oxygenation and ozonation. “Extracorporeal” just means outside the body. During a session, your blood flows out through one IV line, passes through a special diffuser where it meets ozone, and then flows back in through a second line. At our clinic, it also passes under full-spectrum light on the way back.
A research team in Siena, Italy, first used the name EBOO in a 2000 report. You may also see it called EBO2. It is the same idea with a newer spelling (here is how EBOO and EBO2 compare). Many people choose EBOO as part of a wellness and longevity routine.
Why people with Lyme disease ask about EBOO
Lyme disease comes from bacteria spread by tick bites. Doctors usually treat it with antibiotics, and many people feel better. Some people keep feeling tired, achy or foggy for months after treatment. Doctors sometimes call this post-treatment Lyme disease syndrome.
Living with that is hard. It makes sense to look for options that help you feel more like yourself. Many people find EBOO online, read big promises, and then call us to ask what is real. We are glad when you do.
Can EBOO help Lyme disease? What research shows so far
You may see bold claims online about ozone and Lyme bacteria. Those claims go well beyond what research shows today. Here is what we can say plainly:
- Researchers are exploring how ozone interacts with blood. Much of that work is in labs or in small groups of people.
- We know of no large, high-quality studies of EBOO in people with Lyme disease.
- Reports from practitioners are a starting point for questions, not answers.
What we hear from patients is simpler. Some people tell us they feel more energy afterward, or that they enjoy the calm, restful day. Everyone responds differently, and we will never promise you a result.
How EBOO fits with your Lyme care
Your Lyme doctor stays your Lyme doctor. EBOO, if it fits you, sits alongside the care you already get. Keep taking your medicines exactly as prescribed. Bring your medication list to your wellness call so we can review it with you.
With your permission, we are happy to coordinate with your other doctors and share your lab results. Many people like knowing their whole team is on the same page.
What your EBOO day looks like at CPRC
Here is your visit, step by step, so nothing feels like a surprise.
- Free wellness call. We get to know you, answer your questions and go over your health history. Nothing gets booked until you feel ready.
- Quick labs. A simple blood draw checks your CBC, CMP and G6PD. Your provider reviews the results before your EBOO day.
- PEMF mat. Your visit starts on a PEMF mat. Gentle magnetic pulses help you settle in and relax.
- EBOO with full-spectrum light. We place two IV lines, one out and one in. A few liters of your blood loop slowly through a special diffuser, where it meets ozone, then pass under full-spectrum light and flow back to you. You rest in a comfy recliner the whole time.
- NEO red light bed. Next, you unwind in our NEO red light bed. Many people say this is their favorite part.
- IV. An IV gives you fluids and nutrients before you head out.
- Power Plate. You finish with a few minutes of gentle vibration on the Power Plate to get you up and moving for the trip home.
EBOO at Charleston Pain Relief Center is overseen by Kayla Blann, FNP-C. Want more detail? Read our full EBOO guide.
Who EBOO is not a good fit for
Your provider screens everyone before EBOO. That is what the labs and the health history are for. EBOO is not a good fit if you:
- Have a bleeding or clotting condition
- Are pregnant
- Have G6PD deficiency (the G6PD lab checks for this)
Tell us about every medicine you take, including blood thinners, and about any recent illness. If EBOO is not right for you, we will tell you honestly and talk about other options. You can read more on our EBOO safety page.
Coming from out of town? You are in good company
More than half of our EBOO patients travel to see us, and we love that. We help you plan your labs, your visit and your timing, so the trip feels easy. If you are coming in for Lyme questions, bring any recent lab work and notes from your doctor. Our clinic is at 2294 Otranto Rd in North Charleston, SC, close to I-26 and the airport.
Frequently asked questions
Can EBOO treat Lyme disease?
EBOO is a wellness service, not a treatment for Lyme disease. Some people with lingering Lyme symptoms choose it as part of their wellness routine. Your Lyme doctor stays in charge of your Lyme care.
Is there research on EBOO for Lyme disease?
Research is still early. Most of what exists is lab work, small studies and practitioner reports. We know of no large studies of EBOO in people with Lyme.
Do I need to stop my Lyme medicine before EBOO?
Keep taking your medicines exactly as your doctor prescribed. Bring your medication list to your free wellness call, and your provider will review it with you.
What labs do I need before EBOO?
We check a CBC, a CMP and G6PD. Your provider reviews these with your health history to make sure EBOO is a good fit for you.
How long is an EBOO day?
Plan on a few hours. EBOO is part of a full visit with PEMF, red light, an IV and Power Plate. We will give you your exact timing on your free call.
I live out of town. Can I still come?
Yes. More than half of our EBOO patients travel to see us. We help you plan your labs and your visit so the trip feels easy.
Questions about EBOO and Lyme? Let’s talk.
Text us at 843-604-2276 — we’ll answer your questions first. Your text is already written. Just press send.
Rather talk it through? Book a free wellness call.
Keep reading
- EBOO therapy in North Charleston: the full guide
- Can EBOO help chronic conditions? Lyme and autoimmune Q&A
- EBOO safety: what to know
- EBOO vs EBO2: what is the difference?
Charleston Pain Relief Center · 2294 Otranto Rd, North Charleston, SC 29406 · 843-604-2276 · Last updated 30 October 2026. This article is for education and does not replace advice from your own doctor.